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plural Mistresses
(archaic) Used as the title of a married woman before her name. Now used only in the abbreviated form Mrs. quotations
The sound of Mistress Affery cautiously chaining the door before she opened it, caused them both to look that way.
1855 December – 1857 June, Charles Dickens, “The Dreams of Mrs. Flintwinch Thicken”, in Little Dorrit, London: Bradbury and Evans, […], published 1857, book the second (Riches), page 408
(BDSM) Used as the title of a female dominant. examples